Research

Published Work & Work in Progress

Published

Neurodegeneration as Thermodynamic Failure

A Unified Framework for Alzheimer’s, Parkinson’s, ALS, and Huntington’s Disease

We demonstrate that four neurodegenerative diseases are not independent molecular accidents — they are four failure modes of a single dissipative field equation. The collapse index \(\Phi\) measures the thermodynamic distance to the point of no return.

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Entropic I-Field Theory

Fundamental Irreversibility in Field Dynamics

The foundational paper establishing the I-field as a fundamental physical variable, prior to any statistical averaging. Derives the master equation from first principles and establishes three bridges to physical observables.

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In Preparation

Representational Drift as Thermodynamic Necessity

I-Field Framework Applied to Neural Population Codes

We prove that representational drift — the spontaneous reorganisation of neural codes — is a thermodynamic necessity. The drift rate scales as \(\Delta \propto \kappa/m^2\), with direct predictions for Alzheimer’s disease and depression.

Manuscript in preparation · 2025

All papers are published as open-access preprints on Zenodo under CC BY 4.0.